A Comparative Study of Serum Uric Acid Level in Normal Pregnancy, and Pregnancy Induced Hypertension

Hypertension is one of the common complications met with in pregnancy and contributes significantly to the cause of maternal and perinatal morbidity and mortality. The study of uric acid in serum is an interesting problem especially in normal pregnancy and pregnancy induced hypertension (PIH). The present study was carried out at Physiology Department, Shri M. P. Shah Medical College and Guru Gobind Singh Hospital, Jamnagar on Total 80 subjects. Determination of uric acid was carried out by quantitative estimation on colorimetric method by enzymatic uricase method. Results shows that Serum uric acid levels in both the time (predelivery and postdelivery) were statistically significant in Pregnancy induced hypertension than normal pregnancy. Many patients had predisposing factor to development of preeclampsia like primigravida. It is also evident that severity of proteinuria increases with diastolic blood pressure and Levels of serum uric acid did show a high positive correlation with the severity of Pregnancy induced hypertension in relation to hypertension and proteinuria 65% of patients of PIH