Drug Reaction with Eosinophilia and Systemic Syndrome: Systemic Drug Reaction

Drug reaction with eosinophilia and systemic (DRESS) syndrome is a severe systemic drug reaction with a reported mortality of 10%⁵. The estimated incidence of this syndrome ranges from 1 in 1000 to 1 in 10,000 drug exposures. The syndrome consists of a severe skin eruption, fever, hematologic abnormalities (eosinophilia or atypical lymphocytes), and internal organ involvement. Here, we report a case of DRESS syndrome in a young male who presented with acute hepatitis.